diff --git a/src/video_core/engines/maxwell_3d.cpp b/src/video_core/engines/maxwell_3d.cpp
index 2cd595f26b..5ae836acae 100644
--- a/src/video_core/engines/maxwell_3d.cpp
+++ b/src/video_core/engines/maxwell_3d.cpp
@@ -108,8 +108,16 @@ void Maxwell3D::WriteReg(u32 method, u32 value, u32 remaining_params) {
         debug_context->OnEvent(Tegra::DebugContext::Event::MaxwellCommandLoaded, nullptr);
     }
 
+    u32 old = regs.reg_array[method];
     regs.reg_array[method] = value;
 
+    if (value != old) {
+        if (method >= MAXWELL3D_REG_INDEX(vertex_attrib_format) &&
+            method < MAXWELL3D_REG_INDEX(vertex_attrib_format) + regs.vertex_attrib_format.size()) {
+            dirty_flags.vertex_attrib_format = true;
+        }
+    }
+
     switch (method) {
     case MAXWELL3D_REG_INDEX(macros.data): {
         ProcessMacroUpload(value);
diff --git a/src/video_core/engines/maxwell_3d.h b/src/video_core/engines/maxwell_3d.h
index 0509ba3a27..557795d0f7 100644
--- a/src/video_core/engines/maxwell_3d.h
+++ b/src/video_core/engines/maxwell_3d.h
@@ -1004,6 +1004,12 @@ public:
     State state{};
     MemoryManager& memory_manager;
 
+    struct DirtyFlags {
+        bool vertex_attrib_format = true;
+    };
+
+    DirtyFlags dirty_flags;
+
     /// Reads a register value located at the input method address
     u32 GetRegisterValue(u32 method) const;
 
diff --git a/src/video_core/renderer_opengl/gl_rasterizer.cpp b/src/video_core/renderer_opengl/gl_rasterizer.cpp
index bb263b6aae..1bdd4c0544 100644
--- a/src/video_core/renderer_opengl/gl_rasterizer.cpp
+++ b/src/video_core/renderer_opengl/gl_rasterizer.cpp
@@ -33,7 +33,8 @@ using Maxwell = Tegra::Engines::Maxwell3D::Regs;
 using PixelFormat = VideoCore::Surface::PixelFormat;
 using SurfaceType = VideoCore::Surface::SurfaceType;
 
-MICROPROFILE_DEFINE(OpenGL_VAO, "OpenGL", "Vertex Array Setup", MP_RGB(128, 128, 192));
+MICROPROFILE_DEFINE(OpenGL_VAO, "OpenGL", "Vertex Format Setup", MP_RGB(128, 128, 192));
+MICROPROFILE_DEFINE(OpenGL_VB, "OpenGL", "Vertex Buffer Setup", MP_RGB(128, 128, 192));
 MICROPROFILE_DEFINE(OpenGL_Shader, "OpenGL", "Shader Setup", MP_RGB(128, 128, 192));
 MICROPROFILE_DEFINE(OpenGL_UBO, "OpenGL", "Const Buffer Setup", MP_RGB(128, 128, 192));
 MICROPROFILE_DEFINE(OpenGL_Index, "OpenGL", "Index Buffer Setup", MP_RGB(128, 128, 192));
@@ -122,11 +123,16 @@ RasterizerOpenGL::RasterizerOpenGL(Core::Frontend::EmuWindow& window, ScreenInfo
 
 RasterizerOpenGL::~RasterizerOpenGL() {}
 
-void RasterizerOpenGL::SetupVertexArrays() {
-    MICROPROFILE_SCOPE(OpenGL_VAO);
-    const auto& gpu = Core::System::GetInstance().GPU().Maxwell3D();
+void RasterizerOpenGL::SetupVertexFormat() {
+    auto& gpu = Core::System::GetInstance().GPU().Maxwell3D();
     const auto& regs = gpu.regs;
 
+    if (!gpu.dirty_flags.vertex_attrib_format)
+        return;
+    gpu.dirty_flags.vertex_attrib_format = false;
+
+    MICROPROFILE_SCOPE(OpenGL_VAO);
+
     auto [iter, is_cache_miss] = vertex_array_cache.try_emplace(regs.vertex_attrib_format);
     auto& VAO = iter->second;
 
@@ -175,8 +181,13 @@ void RasterizerOpenGL::SetupVertexArrays() {
         }
     }
     state.draw.vertex_array = VAO.handle;
-    state.draw.vertex_buffer = buffer_cache.GetHandle();
     state.Apply();
+}
+
+void RasterizerOpenGL::SetupVertexBuffer() {
+    MICROPROFILE_SCOPE(OpenGL_VB);
+    const auto& gpu = Core::System::GetInstance().GPU().Maxwell3D();
+    const auto& regs = gpu.regs;
 
     // Upload all guest vertex arrays sequentially to our buffer
     for (u32 index = 0; index < Maxwell::NumVertexArrays; ++index) {
@@ -203,6 +214,9 @@ void RasterizerOpenGL::SetupVertexArrays() {
             glVertexBindingDivisor(index, 0);
         }
     }
+
+    // Implicit set by glBindVertexBuffer. Stupid glstate handling...
+    state.draw.vertex_buffer = buffer_cache.GetHandle();
 }
 
 DrawParameters RasterizerOpenGL::SetupDraw() {
@@ -620,7 +634,8 @@ void RasterizerOpenGL::DrawArrays() {
 
     buffer_cache.Map(buffer_size);
 
-    SetupVertexArrays();
+    SetupVertexFormat();
+    SetupVertexBuffer();
     DrawParameters params = SetupDraw();
     SetupShaders(params.primitive_mode);
 
diff --git a/src/video_core/renderer_opengl/gl_rasterizer.h b/src/video_core/renderer_opengl/gl_rasterizer.h
index 60e7838036..5eee5f0888 100644
--- a/src/video_core/renderer_opengl/gl_rasterizer.h
+++ b/src/video_core/renderer_opengl/gl_rasterizer.h
@@ -207,7 +207,8 @@ private:
 
     std::size_t CalculateIndexBufferSize() const;
 
-    void SetupVertexArrays();
+    void SetupVertexFormat();
+    void SetupVertexBuffer();
 
     DrawParameters SetupDraw();